Preheat oven to 350°F. Spray a 9x5-inch loaf pan with cooking spray.
In a large bowl, combine the pumpkin, bananas, eggs, sugars, butter, and vanilla. Stir with a whisk to combine. Set aside.
1 15-ounce can pure pumpkin, 2 medium ripe bananas, mashed, 2 eggs, lightly beaten, 1 cup sugar, ½ cup brown sugar, ½ cup unsalted butter, melted and cooled, 2 teaspoons vanilla
In a medium bowl, combine the flour, baking soda, pumpkin pie spice, and salt. Stir with a whisk to combine.
2 cups flour, 2 teaspoons baking soda, 2 teaspoons pumpkin pie spice, 1 ½ teaspoons salt
Fold the flour mixture into the pumpkin mixture, using a rubber spatula, and mix just until combined. Pour or spoon into the prepared loaf pan. Bake in the preheated 350°F oven for 1 hour 20 minutes or until a toothpick inserted in the center comes out mostly clean.
Remove from the oven and let it cool in the pan for 10 minutes. Remove from the pan and let it cool completely on a cooling rack.